Open Access Research article

Quality evaluation of various commercial specifications of Polygoni Multiflori Radix and its dregs by determination of active compounds

Zhitao Liang*, Ngon-ngon Leung, Hubiao Chen and Zhongzhen Zhao*

Author Affiliations

School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Special Administrative Region, People's Republic of China

For all author emails, please log on.

Chemistry Central Journal 2012, 6:53  doi:10.1186/1752-153X-6-53

Published: 8 June 2012

Abstract

Background

According to market investigation, two kinds of Polygoni Multiflori Radix decoction pieces with different specifications are commercially available: irregular thick slices (0.7-1.3 cm) and length-wise into thin slices (0.11-0.2 cm). The objective of this study was to evaluate the quality of various samples of Polygoni Multiflori Radix decoction pieces and its dregs.

Results

A simple and reliable high performance liquid chromatographic method was developed for determination the contents of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D- glucopyranoside (THSG), emodin and physcion, which were considered to be potent active ingredients. The results showed that the contents of THSG, emodin and physcion varied in samples of different diameters and thicknesses. The results also indicated the dregs of Polygoni Multiflori Radix still contained a considerable amount of THSG, emodin and physcion.

Conclusion

The various commercial specifications of Polygoni Multiflori Radix sold in the markets did not correlate with their prices, and the dregs of Polygoni Multiflori Radix can be further utilized.

Keywords:
Polygoni Multiflori Radix; Decoction pieces; Dreg; Processing; THSG; Emodin; Physcion; HPLC