Open Access Methodology

A highly efficient green synthesis of 1, 8-dioxo-octahydroxanthenes

Andivelu Ilangovan1*, Subramani Malayappasamy1, Samraj Muralidharan1 and Sundaram Maruthamuthu2

Author Affiliations

1 School of Chemistry, Bharathidasan University, Tiruchirappalli - 620024, India

2 Corrosion Protection Division, Central Electro Chemical Research Institute, Karaikudi-630 006, India

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Chemistry Central Journal 2011, 5:81  doi:10.1186/1752-153X-5-81

Published: 8 December 2011

Abstract

SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The same reaction in water, at room temperature gave only the open chain analogue of 1,8-dioxo-octahydroxanthene. Use of eco-friendly green Lewis acid, readily available catalyst and easy isolation of the product makes this a convenient method for the synthesis of either of the products.

Graphical abstract