A highly efficient green synthesis of 1, 8-dioxo-octahydroxanthenes
1 School of Chemistry, Bharathidasan University, Tiruchirappalli - 620024, India
2 Corrosion Protection Division, Central Electro Chemical Research Institute, Karaikudi-630 006, India
Chemistry Central Journal 2011, 5:81 doi:10.1186/1752-153X-5-81Published: 8 December 2011
SmCl3 (20 mol%) has been used as an efficient catalyst for reaction between aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione at 120°C to give 1,8-dioxo-octahydroxanthene derivatives in high yield. The same reaction in water, at room temperature gave only the open chain analogue of 1,8-dioxo-octahydroxanthene. Use of eco-friendly green Lewis acid, readily available catalyst and easy isolation of the product makes this a convenient method for the synthesis of either of the products.