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700 MHz Proton-Proton Nuclear Overhauser Interaction Peaks a for Cyclopamine in CD2Cl2 at 25°C |
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| No.b |
Atom 1 |
Atom 2 |
Relationship |
|
|
|||
| 1 |
1 ax |
3 |
ax-ax |
| 2 |
1 ax |
9 |
ax-ax |
| 3 |
2 ax |
4 ax |
ax-ax |
| 4 |
2 ax |
19 |
ax-ax |
| 5 |
4 eq |
6 |
eq-eq |
| 6 |
8 |
19 |
ax-ax |
| 7 |
8 |
7 e |
ax-eq |
| 8 |
8 |
15 ax |
ax-ax |
| 9 |
9 |
7 ax |
ax-eq |
| 10 |
9 |
14 |
ax-ax |
| 11 |
16 eq |
23 |
eq-ax |
| 12 |
16 ax |
14 |
ax-ax |
| 13 |
18 |
20 |
eq-eq |
| 14 |
18 |
22 |
eq-ax |
| 15 |
19 |
1 ax |
ax-ax |
| 16 |
19 |
4 ax |
ax-ax |
| 17 |
19 |
11 ax |
ax-ax |
| 18 |
20 |
22 |
eq-ax |
| 19 |
21 |
16 eq |
ax-eq |
| 20 |
21 |
16 ax |
ax-ax |
| 21 |
21 |
23 |
ax-ax |
| 22 |
24 eq |
23 |
eq-ax |
| 23 |
24 ax |
18 (vwc) |
ax-eq |
| 24 |
24 ax |
26 ax |
ax-ax |
| 25 |
24 ax |
22 |
ax-ax |
| 26 |
24 ax |
23 (vwc) |
ax-eq |
| 27 |
26 ax |
22 |
ax-ax |
| 28 |
25 |
23 |
ax-ax |
| 29 |
25 |
24 eq |
ax-eq |
| 30 |
25 |
26 eq |
ax-eq |
| 31 |
27 |
24 eq |
eq-eq |
| 32 |
27 |
24 ax |
eq-ax |
| 33 |
27 |
26 eq |
eq-eq |
| 34 |
27 |
26 ax |
eq-ax |
| 35 |
20 |
16 ax (vwc) |
eq-ax |
| 36 |
8 |
11 ax |
ax-ax |
|
aOnly the NOEs that were used to obtain hydrogen and stereochemical assignments are included. bNumbering scheme corresponds to NOESY peaks identified in Additional files 3, 4, 5. cvery weak | |||
Oatis et al. Chemistry Central Journal 2008 2:12 doi:10.1186/1752-153X-2-12 |
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